Given the ever-increasing advances in our ability to diagnose and treat complex cardiovascular disease, it is incumbent on those who provide patient care to remain at the top of their game. The Scottsdale Interventional Forum 2019 (SIF 2019) is designed to fill this need. This comprehensive, state of the art four-day symposium provides an in-depth review of the most relevant advances in the treatment of heart and vascular disease. The organizing committee for SIF 2019 has committed itself to creating a complete, all encompassing curriculum to meet the needs of cardiovascular specialists attending this nationally recognized educational event. Now in it’s 15th year, SIF 2019 will again utilize a talented, world class faculty to provide an in-depth understanding of pathologic disease mechanisms, advanced diagnostic imaging, a Heart Team approach to problem solving as well as an update of the most innovative therapeutic options for complex disease management. The educational means by which this is accomplished includes didactic lectures and case presentations from the world’s experts along with live case transmissions from leading centers throughout the country. This synthesis of a concentrated educational experience and expert commentary from a distinguished faculty provides a superb learning environment for physicians, nurses and allied health professionals. As in past years, SIF 2019 will include a variety of hands-on workshops and specialty symposia. Given the rapid evolution in diagnostic and therapeutic strategies for treating coronary artery disease patients, the SIF Faculty covers the most pertinent diagnostic studies and management issues pertaining to complex coronary intervention. The treatment of unprotected left main disease, chronic total occlusions (CTO’s), and an expert review of novel DES platforms will be featured in both the didactic and live case sessions. Amongst those sessions highlighted at this years Forum will be the use of Impella and other methodologies for circulatory support; the nation’s experts in advanced mechanical circulatory support will provide a day long session in complex percutaneous coronary intervention. Attendees will have an “up close and personal” access to these experts during the four-day meeting. There is a growing need for the interventional cardiologist to understand the management options for atrial fibrillation, traditionally the domain of rhythm management specialists. With growing interest in mechanical left atrial appendage therapies SIF will feature live cases and a lecture series on left atrial appendage closure. Watchman and other devices currently being studied will be discussed in didactic lecture form as well as live case presentations. As renal denervation has evolved into a more realistic and viable therapeutic option for hypertension patients we will examine the ongoing interest in this technology. There may be no field of research more exciting for cardiovascular specialists and more relevant to an aging US demographic than the diagnosis and management of patients with valvular heart disease. Understanding newer modalities and technological breakthroughs in catheter-based therapy of valvular heart disease will be emphasized in multiple sessions. A transcatheter aortic valve replacement (TAVR) symposium will highlight best practice for patients with severe aortic stenosis and also cover important topics such as bicuspid aortic valve disease, transcatheter therapies for aortic insufficiency and also relevant discussions related to the economics of this field. There has been a tremendous interest in the treatment of those stricken with mitral and tricuspid valvular heart disease. Developing a consensus on the best management of those with degenerative mitral valve disease is essential. Practitioners are challenged by the decision as to which mechanical therapy for functional mitral regurgitation might provide the most durable results for patients. These topics will receive in depth analysis by our panel of world experts. Finally, the emerging transcatheter therapies for a burgeoning population with tricuspid and pulmonic valvular disease will be covered in a comprehensive review. In summary, SIF 2019 is intended to provide physicians, nurses, and allied health attendees the most comprehensive and state-of-the-art review of diagnostic and management strategies for the treatment of those afflicted with advanced cardiovascular disorders. The goals of this meeting are simple: Provide the requisite skills to advance bedside patient management, apply innovative therapies in the most practical manner and quantifiably improve the outcomes of our patients suffering from cardiovascular disease.